Start in the middle and ride a pre-determined route. Then go full rich (bottom clip) and do the same route at the same pace. Better or worse? Try at full lean (top clip) Better or worse? Then work you way back towards the middle where it is best behaved most of the time.
You should feel the difference coming off of idle through about 3/4 throttle, so don't be in a hurry to go WOT, ride like you like to ride. Hunting, searching and roughness are usually lean. Muddy, flat and unresponsive are usually rich.
Do yourself a favor and make sure timing, valves, etc are all spot on before you begin this adventure.
Never underestimate the laxative properties of motorcycling.