I've had no issues with vibration. 25,000 miles on the '06 DR.
Sargent saddle, lowered pegs, ProTaper bars, improved front and rear springs, DirtBagz+DirtBagz Duffle, IMS tank, Wolfman Enduro tankbag, Aerostich heated grip covers and bib for warmth. I like the Shinko 705s for road riding but I am running D606s now. I have 3 windshields: Tombstone, MRA Streetshield, and a Parabellum but I mostly ride naked, I mean on the naked bike. The tombstone is terrible, Steetshield takes the wind off your chest but is noisy. Parabellum is a good road windshield but kinda like a guillatine (sp?) off road. After all that I prefer clean air.
The DR is like a Swiss Army Knife. Does it all. Love it.