I have Mapsource 6.16.1 on one computer and I think one rev newer on my Notebook.
I went back and looked at your description of the route. I had to do some searching. I found a place called Bennet's Well and I found Redland's Canyon. My National Parks 24k topos show a road most of the way thru Redlands Canyon but only to a spring and not on out to Panamint.
I only have Topos West for outside the Park, but I will look for some of your other key points later.