The sum of parts is all in the unsprung weight. When I went from a tubed tyre to tubeless and junked the heavy duty tube on the rear wheel on my 1985 R80 monolever I threw away 3.65 lbs of weight. I would rather look at weight savings elsewhere on the bike, it can be done.
R80 Monolever roadbike = 175kg dry with an empty tank (385lbs for you imperial guys) I got another 6kg to go - 169kg no fuel. However I will not be reverse engineering important mechanical bits & pieces I know not much about. If you are obsessed with weight reduction (so am I) lets start with the easy bits.