For those who are interested, here is a blog entry
from an individual who has put over 7,000 miles of mostly highway miles on a set of Anakee 3s, including pictures of the tread (which looks great, but notice he runs his tire pressure pretty high). He rode a GSA in the Iron Butt Rally in 2011 using Anakee 2s.
Handling is great and the new tread design seems less noisy and smoother than the Anakee IIs. Cornering, dry or wet, is rock solid. And, I did notice better handling in the couple of times I went off pavement into the loose stuff.