Knobby tires & The Dempster
A group of us did the ride to Inuvik in early June. We had to wait for the Peel River ferry to be launched so we could make the run for Inuvik. The first half of the road Dawson to Eagle Plains has a 30 Kilometer section (around 250-300 K markers) that when wet was really greasy and I mean nasty, black & evil. I was running TKC80s and the others were on Dunlop 606s even with these tires the road had sections that were butt clenching-ly terrifying. We passed 2 fellow adventure riders on the way in, when they made Eagle Plains they'd had enough and next morning they turned around. They were running 50/50 tires and frankly they suck when the Dempster is wet.
If you somehow have good weather the whole way you can do the whole Dempster Highway in 9-10 hours we did on the way out.