I currently own a FI and Carb'd bike..
While I love the Carb'd bike, I don't trust it enough to take me from Houston to Colorado, Where the FI Bike, I trust it to take me anywhere.
yes I've had mechanical issues with both bikes, but the FI bike was a simple sucking in of the gasket (If anyone knows why the hell the 1200S Guzzi's do that, please do tell.)
And the Carb'd bike had a range of problems from Electrical to Mechanical.
on a Minor note, I love how on Modern bikes with LCD Screens, how if you have an Electrical issue--you can look it up on the computer, Very handy feature and no need to just go searching from square 1.
1977 Kawasaki KZ1000
2008 MotoGuzzi 1200 Sport