i went to botswana recently and had 3 punctures on a deserted 300km stretch of road. up untill then, my tyre changing ability was limited to mountainbikes (though i recon this was good groundwork). i learned pretty quickly how to do it with 2 tyre levers.
i didnt find as difficult to do, as much as i found it a pain in the ass.
tubed tyres suck!
i used to have a quadbike with tubeless wheels. if you get a flat, you plug it in 45seconds max. a tubed tyre fix takes about 45minutes to 2 hours in the bush.