I think a DR650 vs. WR250R comparison makes some sense. One of the main reasons dual sports have grown to over 600cc is for highway travel. Unfortunately, along the way they passed the 300 pound wet threshold and became less suitable for tough trails.
Now along comes the WR250R with several road tests and many threads on ADVrider and Thumpertalk all raving about the wide ratio 6-speed, the silky smooth engine, and the unusual horsepower for a 250. If we have a 300 pound wet motorcycle that rivals the 650 class for freeway comfort, it seems to me the discussion is worth having.
I guess the next question would be which would bother you more on a gnarly trail -- the Suzuki's extra 60-70 pounds of weight or the WR's 125 motocross bike style powerband? I don't think there's any question that a WR250R would spank a DR650 on a motocross track.